Resolution: 2.58 Å
EM Method: Single-particle
Fitted PDBs: 8pk9
Q-score: 0.661
Schulz V, Steinhilper R, Oltmanns J, Freibert SA, Krapoth N, Linne U, Welsch S, Hoock MH, Schunemann V, Murphy BJ, Lill R
Nat Commun (2024) 15 pp. 3269-3269 [ Pubmed: 38627381 DOI: doi:10.1038/s41467-024-47310-8 ]
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Iron-bound human nfs1-isd11-acp1-iscu2-fxn (fe-niaux) complex during persulfide transfer (Complex from Homo sapiens)
- Cysteine desulfurase (44 kDa, Protein from Homo sapiens)
- Frataxin mature form (14 kDa, Protein from Homo sapiens)
- Lyr motif-containing protein 4 (13 kDa, Protein from Homo sapiens)
- Acyl carrier protein (8 kDa, Protein from Escherichia coli BL21(DE3))
- Iron-sulfur cluster assembly enzyme iscu (15 kDa, Protein from Homo sapiens)
- Fe (ii) ion (55 Da, Ligand)
- Water (18 Da, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 8pka
Q-score: 0.624
Schulz V, Steinhilper R, Oltmanns J, Freibert SA, Krapoth N, Linne U, Welsch S, Hoock MH, Schunemann V, Murphy BJ, Lill R
Nat Commun (2024) 15 pp. 3269-3269 [ Pubmed: 38627381 DOI: doi:10.1038/s41467-024-47310-8 ]
- Acyl carrier protein (Complex from Escherichia coli BL21(DE3))
- Pyridoxal-5'-phosphate (247 Da, Ligand)
- Iron-bound human nfs1-isd11-acp1-iscu2-fxn (fe-niaux) complex during persulfide transfer (Complex)
- Iron-sulfur cluster assembly enzyme iscu (15 kDa, Protein from Homo sapiens)
- Lyr motif-containing protein 4 (13 kDa, Protein from Homo sapiens)
- Acyl carrier protein (8 kDa, Protein from Escherichia coli BL21(DE3))
- Cysteine desulfurase (44 kDa, Protein from Homo sapiens)
- Fe (ii) ion (55 Da, Ligand)
- Cysteine desulfurase, lyr motif-containing protein 4 and iron-sulfur cluster assembly enzyme iscu (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
Roco protein from C. tepidum in the GTP state bound to an activating Nanobody
Galicia C, Guaitoli G, Fislage M, Gloeckner CJ, Versees W
eLife (2024) 13 [ Pubmed: 38666771 DOI: doi:10.7554/eLife.94503 ]
Roco protein from C. tepidum in the GTP state bound to the activating Nanobodies NbRoco1 and NbRoco2
Galicia C, Guaitoli G, Fislage M, Gloeckner CJ, Versees W
eLife (2024) 13 [ Pubmed: 38666771 DOI: doi:10.7554/eLife.94503 ]
- Nbroco2 (Protein from Lama glama)
- Ctroco (Protein from Chlorobaculum tepidum)
- Ctroco in the active gtp state bound to the two activating nanobodies nbroco1 and nbroco2 (150 kDa, Complex from Chlorobaculum tepidum)
- Nbroco1 (Protein from Lama glama)
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 8r4b
Q-score: 0.447
Galicia C, Guaitoli G, Fislage M, Gloeckner CJ, Versees W
eLife (2024) 13 [ Pubmed: 38666771 DOI: doi:10.7554/eLife.94503 ]
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
- Rab family protein (124 kDa, Protein from Chlorobaculum tepidum)
- Ctroco in the active gtp state bound to the two activating nanobodies nbroco1 and nbroco2 (150 kDa, Complex from Chlorobaculum tepidum)
- Nbroco2 (14 kDa, Protein from Lama glama)
- Nbroco1 (15 kDa, Protein from Lama glama)
Resolution: 3.55 Å
EM Method: Single-particle
Fitted PDBs: 8r4c
Q-score: 0.54
Galicia C, Guaitoli G, Fislage M, Gloeckner CJ, Versees W
eLife (2024) 13 [ Pubmed: 38666771 DOI: doi:10.7554/eLife.94503 ]
- Nbroco2 (14 kDa, Protein from Lama glama)
- Rab family protein (124 kDa, Protein from Chlorobaculum tepidum)
- Ctroco in the active gtp state bound to the two activating nanobodies nbroco1 and nbroco2 (150 kDa, Complex from Chlorobaculum tepidum)
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 8r4d
Q-score: 0.47
Galicia C, Guaitoli G, Fislage M, Gloeckner CJ, Versees W
eLife (2024) 13 [ Pubmed: 38666771 DOI: doi:10.7554/eLife.94503 ]
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
- Rab family protein (124 kDa, Protein from Chlorobaculum tepidum)
- Ctroco in the active gtp state bound to the two activating nanobodies nbroco1 and nbroco2 (150 kDa, Complex from Chlorobaculum tepidum)
- Nbroco1 (15 kDa, Protein from Lama glama)
Resolution: 4.08 Å
EM Method: Single-particle
Fitted PDBs: 8r8q
Q-score: 0.411
To Be Published
- Major facilitator superfamily domain-containing protein 1 (55 kDa, Protein from Mus musculus)
- Glycosylated lysosomal membrane protein (43 kDa, Protein from Mus musculus)
- Glmp-mfsd1 (Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
